Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering

Abstract Background Diabetes-associated cognitive impairment (DACI) poses a significant challenge to the self-management of diabetes, markedly elevating the risk of adverse complications.A burgeoning body of evidence implicates microglia as a central player in the pathogenesis of DACI.Methods We utilized proteomics to identify potential biomarkers

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Medical Connections and Exchanges in the Early Modern World

For most of human history there have been extensive redken shades 9gi exchanges of medical information all over Eurasia.Some diseases were considered to be geographically determined, and hence had to be cured using local knowledge.Other ailments were found in many places, but accel lifetime horse supplement cures could differ according to location.

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